3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine
CAS: 110522-47-9
Ref. 3D-ND06468
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Informação sobre produto
- 3',5'-Di-O-acetyl-2'-deoxy-5-fluoro-D-uridine3',5'-Di-O-acetyl-5-fluoro-2'-deoxyuridine
- 3',5'-Di-O-Acetyl-5-Fluoro-2'-Deoxy-D-Uridine
- 3',5'-Di-O-acetyl-2'-deoxy-5-fluoro-D-uridine
3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine is an antitumor agent that belongs to the class of heterocyclic ring. It is a pyridinium salt with a benzoic acid residue at position 3 and 5'. The heterocyclic ring is derived from alkylene, which has two double bonds in the chain. This compound has low toxicity and can be synthesized from chloroform, fluorouridine, and pyridine. 3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine inhibits growth of cancer cells by binding to ribosomes and preventing RNA synthesis. It also acts as an alkylating agent that binds to DNA, leading to crosslinking between strands of DNA. This leads to cell death by apoptosis or necrosis due to interference with DNA replication.
Propriedades químicas
Consulta técnica sobre: 3D-ND06468 3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine
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