2',3'-Didehydro-2',3'-dideoxyuridine
CAS: 5974-93-6
Ref. 3D-ND16317
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Informação sobre produto
- 2,4(1H,3H)-pyrimidinedione, 1-[(2R,5S)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-
- 5-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione
- 1-(2,3-Dideoxy-beta-d-glyceropent-2-enofuranosyl)uracil
2',3'-Didehydro-2',3'-dideoxyuridine (DDDU) is a nucleoside analog that inhibits the formation of HIV. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication in cell culture, and has been shown to inhibit the production of HIV-1 virions in vitro. 2',3'-Didehydro-2',3'-dideoxyuridine has been shown to bind to the enzyme glycosyltransferase, which is required for HIV-1 replication. DDU also binds to human CD4+ T cells, deflecting them from the HIV-infected target cell. This compound may be useful as an antiviral agent against HIV-1 infection by inhibiting viral replication and infectivity.
Propriedades químicas
Consulta técnica sobre: 3D-ND16317 2',3'-Didehydro-2',3'-dideoxyuridine
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