5'-Ethylcarboxamidoadenosine

CAS: 35920-39-9

Ref. 3D-NE06155

Informação sobre produto

• Nome: 5'-Ethylcarboxamidoadenosine
• Sinónimos: 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-b-D-ribofuranuronamideNECA5'-Ethylcarboxamido-D-adenosine
• Marca: Biosynth
• Descrição: 5'-Ethylcarboxamidoadenosine (5-ECA) is an adenosine receptor antagonist that is used as a radioligand to study the binding of adenosine and other nucleotides to their receptors. 5-ECA binds to the A3 receptor, which is a member of the G protein-coupled receptor family. This compound also inhibits platelet aggregation and has been shown to have anti-inflammatory effects in mice with colon cancer. 5-ECA was found to inhibit tumor growth in a mouse model system by suppressing IL-2 production and reducing levels of PGE2, an effect that may be due to inhibition of cyclase activity. 5-ECA can be used in vitro for studies on pluripotent cells because it does not affect their ability to differentiate.

Propriedades químicas

• Peso molecular: 308.29 g/mol
• Fórmula: C₁₂H₁₆N₆O₄
• Pureza: Min. 95%
• Cor/forma: White Powder