N6-Etheno 2'-deoxyadenosine
CAS: 68498-25-9
Ref. 3D-NE06241
5mg | 176,00 € | ||
10mg | 237,00 € | ||
25mg | 372,00 € | ||
50mg | 550,00 € | ||
100mg | 655,00 € |
Informação sobre produto
- N6-Etheno 2'-deoxy-D-adenosine
- 1,N(6)-Ethenodeoxyadenosine
- 1,N6-Ethenodeoxyadenosine
- 1,N<sup>6</sup>-Etheno-2′-deoxyadenosine
- 1,N<sup>6</sup>-Etheno-dA
- 1,N<sup>6</sup>-Ethenodeoxyadenosine
- 3-(2-Deoxy-beta-D-erythro-pentofuranosyl)-3H-imidazo(2,1-i)purine
- 3-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-3H-imidazo[2,1-i]purine
- 3-(2-deoxypentofuranosyl)-3H-imidazo[2,1-i]purine
- 3H-Imidazo(2,1-i)purine, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-
- Ver mais sinónimos
- 3H-Imidazo[2,1-i]purine, 3-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-
- Ccris 2746
- Ethenodeoxyadenosine
- N<sup>1</sup>,N<sup>6</sup>-Etheno-2′-deoxyadenosine
N6-Etheno 2'-deoxyadenosine is a nucleoside analogue that inhibits DNA synthesis by binding to the enzyme thymidylate synthase, which catalyzes the conversion of deoxyuridine monophosphate to thymidine monophosphate. This drug has been shown to be genotoxic in vitro and in vivo, as evidenced by its ability to induce chromosomal aberrations in cultured human lymphocytes and disrupt DNA replication in mammalian cells. It also reacts with mismatched base pairs and dna duplexes, leading to their degradation. N6-Etheno 2'-deoxyadenosine binds reversibly to antibodies and can be detected using an analytical method that employs monoclonal antibodies.
Propriedades químicas
Consulta técnica sobre: 3D-NE06241 N6-Etheno 2'-deoxyadenosine
Se desejar solicitar um orçamento ou fazer uma encomenda, por favor, adicione os produtos ao seu carrinho e depois solicite um orçamento ou encomenda a partir do carrinho. É mais rápido, mais barato e poderá beneficiar-se dos descontos e outras vantagens disponíveis.