Inosine 5'-monophosphate disodium salt hydrate

CAS: 4691-65-0

Ref. 3D-NI02985

Informação sobre produto

• Nome: Inosine 5'-monophosphate disodium salt hydrate
• Sinónimos: 5′-IMP di-Na salt, 5′-IMP disodium salt, 5′-Inosinic acid, disodium salt, 5′-Inosinic acid, sodium salt (1:2), Disodium 5′-IMP, Disodium IMP, Disodium inosinate, Disodium inosine 5′-monophosphate, Disodium inosine 5′-phosphate, E 631, E 631 (food enhancement agent), IMP disodium salt, IMP sodium salt, Inosine 5′-monophosphate disodium, Inosine 5′-monophosphoric acid disodium salt, Inosine monophosphate disodium salt, Inosine-5'-monophosphate,disodium salt, NSC 20263, Sodium 5′-inosinate, Sodium inosinate, [[3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)tetrahydrofuran-2-yl]methoxy-sodiooxy-phosphoryl]oxysodium

Descrição

Inosine 5'-monophosphate disodium salt hydrate is a nucleotide that is synthesized from adenosine triphosphate in the energy metabolism of cells. It is used as an activator of signal pathways and as a potent inducer of metabolic enzymes. Inosine 5'-monophosphate disodium salt hydrate has been shown to induce bowel disease in mice with experimental colitis, suggesting its utility for treating inflammatory bowel disease. Inosine 5'-monophosphate disodium salt hydrate binds to the ATP-binding site of GTPase, stimulating the hydrolysis of ATP to ADP and phosphate. This reaction causes a conformational change in the enzyme's active site that increases the affinity for GTP by about 10-fold. The binding site is composed of two alpha helices sandwiching a central beta sheet and the catalytic residues are located at both ends of this beta sheet. Structural analysis has revealed that this drug interacts with

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 392.17 g/mol
• Fórmula: C₁₀H₁₁N₄O₈PNa₂·xH₂O
• Pureza: Min. 99.0 Area-%
• Cor/forma: White Powder