5-Isopropyl-2'-deoxyuridine

CAS: 60136-25-6

Ref. 3D-NI16765

Informação sobre produto

• Nome: 5-Isopropyl-2'-deoxyuridine
• Sinónimos: 2'-Deoxy-5-(1-methylethyl)uridine2'-Deoxy-5-isopropyluridine5-Isopropyldeoxyuridine, 1-(2-deoxypentofuranosyl)-5-(propan-2-yl)pyrimidine-2,4(1H,3H)-dione, 2'-Deoxy-5-Propan-2-Yluridine, 2'-Deoxy-5-isopropyluridine, 2′-Deoxy-5-(1-methylethyl)uridine, 5-Isopropyldeoxyuridine, Epervudina, Epervudina [INN-Spanish], Epervudine [INN], Epervudinum, Epervudinum [INN-Latin], Unii-3G05Ph9Fas, Uridine, 2′-deoxy-5-(1-methylethyl)-

Descrição

5-Isopropyl-2'-deoxyuridine is a nucleoside analog that is used in the treatment of inflammatory bowel disease. It has been shown to be effective in the treatment of Crohn's disease, ulcerative colitis, and indeterminate colitis. 5-Isopropyl-2'-deoxyuridine inhibits bacterial growth by inhibiting RNA synthesis, which leads to cell death. This drug also inhibits the production of inflammatory mediators such as prostaglandins and leukotrienes that are released from cells infected with bacteria. 5-Isopropyl-2'-deoxyuridine is converted into an active form by hydrolysis or oxidation followed by phosphorylation. This drug binds to the 5' end of bacterial DNA and prevents the formation of hydrogen bonds between adjacent bases, causing strand breakage.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 270.28 g/mol
• Fórmula: C₁₂H₁₈N₂O₅
• Pureza: Min. 95%