1-(b-L-Threonyl)-5-methyluracil
Ref. 3D-NT137585
| Tamanho indefinido | A consultar |
Informação sobre produto
1-(b-L-Threonyl)-5-methyluracil (1,5MT) is a synthetic nucleoside that has antiviral and anticancer properties. 1,5MT is modified with a b-L-threonyl group at the 5’ position. This modification stabilizes the molecule and prevents its degradation by ribonucleases. The modification also increases the phosphoramidite reactivity of 1,5MT and enhances its incorporation into DNA during synthesis. 1,5MT is an activator for RNA polymerase II, which plays an important role in transcriptional regulation. It binds to the enzyme's allosteric site and stimulates transcriptional elongation by RNA polymerase II through phosphoramidate formation with deoxyribose phosphate. 1,5MT is active against cancer cells in vitro and has been shown to inhibit tumor growth in vivo.
Propriedades químicas
Consulta técnica sobre: 3D-NT137585 1-(b-L-Threonyl)-5-methyluracil
Se desejar solicitar um orçamento ou fazer uma encomenda, por favor, adicione os produtos ao seu carrinho e depois solicite um orçamento ou encomenda a partir do carrinho. É mais rápido, mais barato e poderá beneficiar-se dos descontos e outras vantagens disponíveis.
