Heparin disaccharide I-S, tetrasodium salt

CAS: 136098-10-7

Ref. 3D-OH28906

Informação sobre produto

• Nome: Heparin disaccharide I-S, tetrasodium salt
• Sinónimos: Delta-Ua-2S->Glcns-6S Na3, Deltaua-2S->Glcns-6S Na4, Disaccharide Ii-S, Disaccharide I-S, Heparin Disaccharide I-S Sodium Salt, Heparin Disaccharide I-S Sodium, (Α-△Ua-2S-[1→4]-Glcns-6S), hexose, 2-deoxy-4-O-(4-deoxy-2-O-sulfohex-4-enopyranuronosyl)-2-(sulfoamino)-, 6-(hydrogen sulfate), monosodium salt

Descrição

Heparin disaccharide I-S, tetrasodium salt is a sodium salt of heparin that has been modified to contain two sulfate groups. The chemical modification of heparin disaccharide I-S, tetrasodium salt alters the molecule's charge and surface properties. This modification increases the molecule's ability to bind with cell surface markers and inhibits the activity of proteases. Heparin disaccharide I-S, tetrasodium salt is able to inhibit leukaemia proliferation in thp-1 cells by binding with cytoskeletal proteins such as vimentin and actin. This chemical also prevents PMA induced morphological changes in thp-1 cells. Heparin disaccharide I-S, tetrasodium salt is used as an anticoagulant in therapeutic settings. It is used to prevent blood clotting by inhibiting the activation of factors Xa and IIa. Heparin disaccharide

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 665.4 g/mol
• Fórmula: C₁₂H₁₅NO₁₉S₃·4Na
• Pureza: Min. 98 Area-%
• Cor/forma: White Powder