Amyloid β-Protein (Human, 1-42) (Bulk)

CAS: 107761-42-2

Ref. 3D-PAM-4349

Informação sobre produto

• Nome: Amyloid β-Protein (Human, 1-42) (Bulk)
• Sinónimos: Beta-Amyloid Peptide (1-42), Human, Daefrhdsgyevhhqklvffaedvgsnkgaiiglmvggvvia, Amyloid Beta-Peptide (1-42) (Human), Amyloid B-Protein Fragment 1-42, Amyloidb-Peptide(1-42)(human), H-Asp-Ala-Glu-Phe-Arg-His-Asp--Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-OH, H-asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Gly-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Ile-Ala-OH, Abeta 1-42, β-Amyloid(1-42)Human

Descrição

Amyloid beta-protein (Aβ) is a peptide that is found in the human brain. It is one of the major components of amyloid plaque, which are deposits of a protein fragment in the brain that form as a result of aging and Alzheimer’s disease. It is produced by cleavage of the amyloid precursor protein (APP). Aβ has been shown to be toxic to cells, causing them to die. This toxicity may be due to its ability to inhibit ATP production and increase oxidative stress. Aβ can also induce apoptosis by binding to receptors on cell surfaces and activating intracellular signaling pathways. These events lead to activation of caspases, which are proteolytic enzymes that contribute to programmed cell death.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 4,514 g/mol
• Fórmula: C₂₀₃H₃₁₁N₅₅O₆₀S
• Pureza: Min. 95%