Informação sobre produto
- 2,2-Dimethyl-N-(2,4,6-Trimethoxyphenyl)-Dodecanamid
- Ci 976
- Dodecanamide, 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-
- Pd 128042
- 2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide
CI 976 is a lipid-lowering agent that inhibits the synthesis of fatty acids and cholesterol. CI 976 inhibits the enzyme activity of acyl-coenzyme A:cholesterol acyltransferase and 3-hydroxy-3-methylglutaryl coenzyme A reductase, which are involved in the synthesis of cholesterol. CI 976 is also an inhibitor of the uptake of glucose, which may be due to its effects on phospholipid membranes. CI 976 has been shown to inhibit the growth factor receptor tyrosine kinase activity in thp-1 cells and it decreases uptake by inducing receptor activity. Furthermore, CI 976 has been shown to have antiatherogenic properties in atherosclerotic lesion models by inhibiting cholesterol esterase activity.
Propriedades químicas
Consulta técnica sobre: 3D-PEA28947 CI 976
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