D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin

CAS: 130308-48-4

Ref. 3D-PKB-4293-V

Informação sobre produto

• Nome: D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin
• Sinónimos: Hoe 140 Icatibant D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg (Thi: L-Thienylalanine, Tic: 1,2,3,4-Tetrahydroisoquinoline-3-Carboxyl ic Acid, Oic: (3aS,7aS)-Octahydroindolyl-2-Carboxylic Acid), Firazyr, Hoe140, L-Arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2alpha,3abeta,7abeta)-octahydro-1H-indole-2-carbonyl-, (2S)-2-({[(3aS,7aS)-1-({2-[(2S)-2-{[(2S)-2-({[({(4R)-1-[(1-{2-({(2R)-2-amino-5-[(diaminomethylidene)amino]pentanoyl}amino)-5-[(diaminomethylidene)amino]pentanoyl}pyrrolidin-2-yl)carbonyl]-4-hydroxypyrrolidin-2-yl}carbonyl)amino]acetyl}amino)-3-(thiophen-2-yl)propanoyl]amino}-3-hydroxypropanoyl]-1,2,3,4-tetrahydroisoquinolin-3-yl}carbonyl)octahydro-1H-indol-2-yl]carbonyl}amino)-5-[(diaminomethylidene)amino]pentanoic acid (non-preferred name)

Descrição

D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin is a synthetic peptide that is used as a research tool. It has been shown to activate ion channels and receptor proteins in studies on cell biology and pharmacology. This peptide also inhibits the binding of ligands to their receptors, which may be due to its structural similarity with other peptides that bind to the same receptor. D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin is an inhibitor of protein interactions.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 1,304.5 g/mol
• Fórmula: C₅₉H₈₉N₁₉O₁₃S
• Pureza: Min. 95%