Ac-FLEAIG-NH2

Ref. 3D-PP48988

Informação sobre produto

• Nome: Ac-FLEAIG-NH2

Descrição

Peptide Ac-FLEAIG-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using Ac-FLEAIG-NH2 include the following: The identification of polymerized and oxidized alpha-1 antitrypsins (ATs) induced by cigarette smoke as proinflammatory factors in the pathogenesis of emphysema Z Li - 2023 - aru.figshare.comhttps://aru.figshare.com/articles/thesis/The_identification_of_polymerized_and_oxidized_alpha-1_antitrypsins_ATs_induced_by_cigarette_smoke_as_proinflammatory_factors_in_the_pathogenesis_of_emphysema/23753238 Targeting serpins in high-throughput and structure-based drug design YP Chang, R Mahadeva, AOM Patschull, I Nobeli - Methods in , 2011 - Elsevierhttps://www.sciencedirect.com/science/article/pii/B9780123859501000080 The structural basis of serpin polymerization studied by hydrogen/deuterium exchange and mass spectrometry Y Tsutsui , B Kuri, T Sengupta , PL Wintrode - Journal of biological chemistry, 2008 - ASBMBhttps://www.jbc.org/article/S0021-9258(20)64654-3/abstract Expression, purification and characterization of recombinant Z alpha1-antitrypsin-the most common cause of alpha1-antitrypsin deficiency V Levina , W Dai, AS Knaupp , D Kaiserman - Protein expression and , 2009 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1046592809001508 Discovery of an inhibitor of Z-alpha1 antitrypsin polymerization V Berthelier, JB Harris , KN Estenson, J Baudry - PLoS One, 2015 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126256 Cellular consequences of Z alpha-1 antitrypsin accumulation and prospects for therapy S Alam, R Mahadeva - HEPATOLOGY, 2013 - researchgate.nethttps://www.researchgate.net/profile/Samuel-Alam/publication/335991396_CELLULAR_CONSEQUENCES_OF_Z_ALPHA-1_ANTITRYPSIN_ACCUMULATION_AND_PROSPECTS_FOR_THERAPY/links/642b1429ad9b6d17dc3208fa/Cellular-Consequences-of-Z-Alpha-1-Antitrypsin-Accumulation-and-Prospects-for-Therapy.pdf 6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization: implications for the prevention of Z alpha1-antitrypsin-related cirrhosis R Mahadeva, TR Dafforn , RW Carrell - Journal of Biological , 2002 - ASBMBhttps://www.jbc.org/article/S0021-9258(19)82219-6/abstract Applications and Improvements in the Molecular Modeling of Protein and Ligand Interactions JB Harris - 2014 - trace.tennessee.eduhttps://trace.tennessee.edu/utk_graddiss/2826/ Serpin polymerization in vitro JA Huntington , M Yamasaki - Methods in Enzymology, 2011 - Elsevierhttps://www.sciencedirect.com/science/article/pii/B9780123859501000171 Z alpha-1 antitrypsin deficiency and the endoplasmic reticulum stress response CM Greene , NG McElvaney - World Journal of Gastrointestinal , 2010 - ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091154/ Protein misfolding and obstructive lung disease CM Greene , NG McElvaney - Proceedings of the American Thoracic , 2010 - atsjournals.orghttps://www.atsjournals.org/doi/abs/10.1513/pats.201002-019AW Misfolding and Polymerisation of Alpha1-Antitrypsin: Conformational Pathology and Therapeutic Targeting B Gooptu , DA Lomas - Alpha-1 Antitrypsin: Role in Health and Disease, 2016 - Springerhttps://link.springer.com/chapter/10.1007/978-3-319-23449-6_3 Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol A Zhou, PE Stein, JA Huntington , RW Carrell - Journal of Biological , 2003 - ASBMBhttps://www.jbc.org/article/S0021-9258(19)30314-X/abstract How small peptides block and reverse serpin polymerisation A Zhou, PE Stein, JA Huntington , P Sivasothy - Journal of molecular , 2004 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0022283604009180

• Marca: Biosynth