Histatin 5

CAS: 104339-66-4

Ref. 3D-PP49102

Informação sobre produto

• Nome: Histatin 5
• Sinónimos: H-DSHAKRHHGYKRKFHEKHHSHRGY-OH, Histatin-5

Descrição

Peptide Histatin 5 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using Histatin 5 include the following: The P-113 Fragment of Histatin 5 Requires a Specific Peptide Sequence for Intracellular Translocation in Candida albicans, Which Is Independent of Cell Wall WS Jang, XS Li, JN Sun - Antimicrobial agents and , 2008 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/aac.01199-07 Pro-oxidant activity of histatin 5 related Cu (II)-model peptide probed by mass spectrometry T Cabras , M Patamia, S Melino , R Inzitari - Biochemical and , 2007 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0006291X07008510 Engineering improved variants of the antifungal peptide histatin 5 with reduced susceptibility to Candida albicans secreted aspartic proteases and enhanced SP Ikonomova , P Moghaddam-Taaheri - The FEBS , 2018 - Wiley Online Libraryhttps://febs.onlinelibrary.wiley.com/doi/abs/10.1111/febs.14327 Effects of histatin 5 modifications on antifungal activity and kinetics of proteolysis SP Ikonomova , P Moghaddam-Taaheri - Protein , 2020 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/pro.3767 Histatin 5-spermidine conjugates have enhanced fungicidal activity and efficacy as a topical therapeutic for oral candidiasis S Tati, R Li, S Puri , R Kumar , P Davidow - Antimicrobial agents , 2014 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/aac.01851-13 Metal-binding and nuclease activity of an antimicrobial peptide analogue of the salivary histatin 5 S Melino , M Gallo, E Trotta, F Mondello , M Paci - Biochemistry, 2006 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bi0615137 Salivary histatin 5: dependence of sequence, chain length, and helical conformation for candidacidal activity. PA Raj, M Edgerton, MJ Levine - Journal of Biological Chemistry, 1990 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0021925819396784 Histatin 5 variant reduces Candida albicans biofilm viability and inhibits biofilm formation P Moghaddam-Taaheri, JA Leissa, HB Eppler - Fungal Genetics and , 2021 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S108718452100013X Adsorption behavior of antimicrobial peptide histatin 5 on PMMA M Yoshinari, T Kato, K Matsuzaka - Research Part B , 2006 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/jbm.b.30393 Peptide self-assembly is linked to antibacterial, but not antifungal, activity of histatin 5 derivatives L Schnaider , A Rosenberg, T Kreiser , S Kolusheva - Msphere, 2020 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/msphere.00021-20 Histatins: antimicrobial peptides with therapeutic potential K Kavanagh , S Dowd - Journal of pharmacy and pharmacology, 2004 - academic.oup.comhttps://academic.oup.com/jpp/article-abstract/56/3/285/6147243 Human antimicrobial peptide histatin 5 is a cell- penetrating peptide targeting mitochondrial ATP synthesis in Leishmania JR Luque-Ortega, W van't Hof, ECI Veerman - The FASEB , 2008 - Wiley Online Libraryhttps://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.07-096081 Uptake of the antifungal cationic peptide Histatin 5 by Candida albicans Ssa2p requires binding to non-conventional sites within the ATPase domain JN Sun, W Li, WS Jang, N Nayyar - Molecular , 2008 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2958.2008.06480.x Protein Engineering Approaches to Improve the Therapeutic Potential of Histatin-5 for Candida albicans Infections JA Leissa - 2019 - search.proquest.comhttps://search.proquest.com/openview/37aeca1b3db842ab6162826337b7c273/1?pq-origsite=gscholar&cbl=18750&diss=y Antifungal Activity and Action Mechanism of Histatin 5-Halocidin Hybrid Peptides against Candida ssp J Han, MA Jyoti , HY Song, WS Jang - PLoS One, 2016 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0150196 Histatin 5-Inspired Short-Chain Peptides Selectively Combating Pathogenic Fungi with Multifaceted Mechanisms G Lu, X Ju, M Zhu, J Ou, D Xu, K Li - Advanced , 2024 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.202303755 Histatin 5-derived peptide with improved fungicidal properties enhances human immunodeficiency virus type 1 replication by promoting viral entry F Groot, RW Sanders, O ter Brake , K Nazmi - Journal of , 2006 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/jvi.00796-06 The human salivary peptide histatin 5 exerts its antifungal activity through the formation of reactive oxygen species EJ Helmerhorst, RF Troxler - Proceedings of the , 2001 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.141366998 The cellular target of histatin 5 on Candida albicans is the energized mitochondrion EJ Helmerhorst, P Breeuwer, W van't Hof - Journal of Biological , 1999 - ASBMBhttps://www.jbc.org/article/S0021-9258(18)37002-9/abstract Reactive oxygen species play no role in the candidacidal activity of the salivary antimicrobial peptide histatin 5 ECI Veerman, K Nazmi, W Van't Hof - Biochemical , 2004 - portlandpress.comhttps://portlandpress.com/biochemj/article-abstract/381/2/447/91289 Whole-genome approach to understanding the mechanism of action of a histatin 5-derived peptide CB Bullock, DS McNabb, I Pinto - Antimicrobial Agents and , 2020 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/aac.01698-19 Relevance of amphiphilicity and helicity on the antibacterial action of a histatin 5-derived peptide C Peggion, V Panetta, L Lastella - Journal of Peptide , 2024 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/psc.3609 Killing of Candida albicans by histatin 5: cellular uptake and energy requirement C Gyurko, U Lendenmann, EJ Helmerhorst - Antonie van , 2001 - Springerhttps://link.springer.com/article/10.1023/A:1012070600340 Effects of histatin 5 and derived peptides on Candida albicans ALA RUISSEN, J GROENINK - Biochemical , 2001 - portlandpress.comhttps://portlandpress.com/biochemj/article-abstract/356/2/361/39284 Histatin 5 and derivatives: Their localization and effects on the ultra-structural level ALA Ruissen, J Groenink, W Van't Hof - Peptides, 2002 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0196978102000761 Candidacidal effects of two antimicrobial peptides: histatin 5 causes small membrane defects, but LL-37 causes massive disruption of the cell membrane AL den HERTOG, J van MARLE - Biochemical , 2005 - portlandpress.comhttps://portlandpress.com/biochemj/article-abstract/388/2/689/93329 Interactions of histatin 5 and histatin 5-derived peptides with liposome membranes: surface effects, translocation and permeabilization AL Den Hertog, HWWF Sang, R Kraayenhof - Biochemical , 2004 - portlandpress.comhttps://portlandpress.com/biochemj/article-abstract/379/3/665/41414

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 3,036.36 g/mol
• Fórmula: C₁₃₃H₁₉₅N₅₁O₃₃