Urotensin II (Human)

CAS: 251293-28-4

Ref. 3D-PUT-4365-V

Informação sobre produto

• Nome: Urotensin II (Human)
• Sinónimos: Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val, 1:PN: JP2002087982 PAGE: 2 claimed protein, 47: PN: WO0031265 SEQID: 3 claimedprotein, Human urotensin II, Urotensin II (human), H-Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH (Disulfide bond)

Descrição

A potent vasoconstrictor, available in the hydrochloride form with disulfide bonds between Cys5-Cys10 and as a 0.5mg vial.
Urotensin II (UT-II) is a peptide that is found in humans and other vertebrates and is involved in biological systems such as the nervous, endocrine, cardiovascular and renal.
Like that of urotensin II-related peptide, urotensin II contains the hexapeptide -CYS-TYR-LYS-TRP-PHE-CYS- known as the core and this is crucial to its biological function. Urotensin II can also increase the concentration of intercellular calcium through binding to its G protein coupled receptor: urotensin-II receptor which causes the activation of Protein kinase C followed by the activation of Phospholipase C.
UT-II is widely distributed throughout the body, with highest concentrations found in the cardiovascular system, particularly in the heart and blood vessels. UT-II has been shown to have a wide range of physiological effects in humans, including vasoconstriction, modulation of blood pressure, and stimulation of the release of aldosterone and vasopressin.
In addition to its physiological effects, UT-II has also been implicated in the pathogenesis of various cardiovascular and metabolic disorders, including hypertension, heart failure, and diabetes. Inhibition of UT-II signaling has been suggested as a potential therapeutic target for these conditions.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 1,388.6 g/mol
• Fórmula: C₆₄H₈₅N₁₃O₁₈S₂
• Pureza: Min. 95%