1-[[4-(4-Chloro-3,5-dimethylphenoxy)phenyl]methyl]-6-(2-furanyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

CAS: 1814891-79-6

Ref. 3D-PXC89179

Informação sobre produto

• Nome: 1-[[4-(4-Chloro-3,5-dimethylphenoxy)phenyl]methyl]-6-(2-furanyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
• Marca: Biosynth
• Descrição: 1-[[4-(4-Chloro-3,5-dimethylphenoxy)phenyl]methyl]-6-(2-furanyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid is a potent blocker of the Kv1.2 voltage gated potassium channel. It has been shown to inhibit the growth of breast cancer cells in vitro and in vivo, and to induce apoptosis by activating caspase 3. This drug also inhibits the activation of NFκB in human monocyte cell cultures, which may be due to its ability to inhibit the binding of nuclear factor kappa B (NFκB) to DNA.

Propriedades químicas

• Peso molecular: 487.9 g/mol
• Fórmula: C₂₇H₂₂ClN₃O₄
• Pureza: Min. 95%