5β-Finasteride
CAS:
Ref. 3D-QFA37522
Informação sobre produto
Nome:5β-Finasteride
Marca:Biosynth
Descrição:5β-Finasteride (5β-F) is a synthetic steroid that inhibits the conversion of testosterone to dihydrotestosterone. It is used in the treatment of benign prostatic hyperplasia and male-pattern hair loss. 5β-F has been shown to be effective against alopecia, as well as other symptoms such as decreased libido and impotence. 5β-F has also been found to inhibit the progesterone receptor with an IC50 value of 3 nM, making it a potential progesterone receptor antagonist. The pharmacokinetics of 5β-F have been studied in rats, showing it is rapidly absorbed from the gastrointestinal tract and metabolized by the liver. The inhibition constant for this drug is 0.2 μM, which makes it a potentiator for drugs such as creatine kinase or phenytoin. The clinical trials on humans show that 5β-F inhibits creatine kinase activity and can potentiate other drugs
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Propriedades químicas
Peso molecular:372.5 g/mol
Fórmula:C23H36N2O2
Pureza:Min. 95%