2-Methoxyphenylmagnesium bromide, 0.5M THF
CAS: 16750-63-3
Ref. 3D-RAA75063
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Informação sobre produto
- Bromo-(2-Methoxyphenyl)Magnesium
Triphosgene is an organometallic compound that reacts with a variety of organic compounds, such as amines, chlorides, and other halides to form cross-coupling products. The reaction is catalyzed by magnesium which activates the triphosgene. Triphosgene reacts with nitrogen nucleophiles (such as ammonia) to produce aryl amines. Triphosgene has been used in the preparation of many pharmaceuticals including antibiotics, hormones, and anti-inflammatory drugs. As an example, it was used in the synthesis of 2-methoxyphenylmagnesium bromide from 2-bromoethanol and phenylmagnesium bromide in THF at 0.5 M concentration at room temperature for 24 hours. This reaction product was then purified by recrystallization from ethanol/ether mixture followed by vacuum drying to yield a white solid product. This reaction was carried out in a sealed tube under
Propriedades químicas
Consulta técnica sobre: 3D-RAA75063 2-Methoxyphenylmagnesium bromide, 0.5M THF
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