2,6-Dimethyl-4-nitroaniline
CAS: 16947-63-0
Ref. 3D-RAA94763
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Informação sobre produto
- 2,6-Dimethyl-4-Nitroaniline
- 2,6-Dimethyl-4-nitro-phenylamine
- 2,6-Dimethyl-4-nitrobenzenamine
- 2,6-Dimethyl-4-nitrophenylamine
- 2,6-Xylidine, 4-nitro-
- 4-Nitro-2,6-Xylidine
- Benzenamine, 2,6-dimethyl-4-nitro-
- NSC 101580
2,6-Dimethyl-4-nitroaniline (DMN) is a nitrosamine that has been found to be a significant contaminant of drinking water. DMN is regulated as an irritant and a probable human carcinogen. The effects of DMN on the body are not fully understood, but it has been shown to cause damage to the liver and kidney in vivo. DMN may act by interfering with the synthesis of DNA or RNA, which can lead to cell death. The proposed mechanism for this is inhibition of the enzyme ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides for DNA synthesis. This mechanism is supported by experiments in rats where DMN was found to inhibit erythrocyte production in vivo.
DMN can also be methylated in vivo by S-adenosylmethionine synthetase, yielding 2-methyl-6-dimethylamino-4
Propriedades químicas
Consulta técnica sobre: 3D-RAA94763 2,6-Dimethyl-4-nitroaniline
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