4-Amino-5-chloro-N-[[(1S,7aS)-hexahydro-1H-pyrrolizin-1-yl]methyl]-2-methoxybenzamide

CAS: 141196-99-8

Ref. 3D-RFA19699

Informação sobre produto

• Nome: 4-Amino-5-chloro-N-[[(1S,7aS)-hexahydro-1H-pyrrolizin-1-yl]methyl]-2-methoxybenzamide
• Sinónimos: benzamide, 4-amino-5-chloro-N-[[(1S,7aS)-hexahydro-1H-pyrrolizin-1-yl]methyl]-2-methoxy-

Descrição

4-Amino-5-chloro-N-[(1S,7aS)-hexahydro-1H-pyrrolizin-1-yl]methyl]-2-methoxybenzamide is a potent and selective activator of the TRPA1 ion channel. It is an inhibitor of the TRPM8 ion channel. This product is supplied as a white to off white crystalline solid.
TRPA1 is activated by chemicals such as cinnamaldehyde, eugenol, and acetaldehyde. It has been shown that TRPA1 plays a role in pain sensation and inflammation. TRPA1 activation can lead to the release of inflammatory mediators such as prostaglandins and histamine from cells present in inflamed tissue.
TRPA1 activation also leads to the release of substance P from nerve endings in pain pathways.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 323.82 g/mol
• Fórmula: C₁₆H₂₂ClN₃O₂
• Pureza: Min. 95%