Informação sobre produto
PF4618433 is a molecule that binds to the tyrosine kinase domain of β-catenin, which is a protein implicated in many cellular processes. PF4618433 inhibits β-catenin's binding to other proteins, including the albumin-binding domain of protocadherin 15 and the kinase domain of insulin receptor substrate 2. These interactions are important for the regulation of cell growth and differentiation. In vitro studies show that PF4618433 inhibits the proliferation and migration of ventricular myocytes. The inhibition may be due to its ability to prevent β-catenin from binding with other proteins, including cadherins and insulin receptors.
PF4618433 is currently being studied as a potential drug target for treatment of heart disease, osteoporosis, neonatal renal failure, and cancer.
Propriedades químicas
Consulta técnica sobre: 3D-RWB39385 PF4618433
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