Informação sobre produto
3-Methyl-1,5-naphthyridine is a 5-hydroxytryptamine (5HT) receptor antagonist that was synthesized and tested for the first time in humans. The pharmacokinetic properties of 3-methyl-1,5-naphthyridine were studied in humans and it was shown that the drug has a short half life of about 1.8 hours after oral administration. It also showed antibacterial efficacy against Escherichia coli and Enterococcus faecalis when tested in vitro. In addition, 3-methyl-1,5-naphthyridine has been shown to inhibit the activity of 5HT2A receptors by binding to them competitively. The molecular modeling studies suggest that 3-methyl-1,5-naphthyridine binds to the microsomal proteins on the surface of bacteria cells with its furyl group. This binding inhibits enzymes such as cholinesterase inhibitors and thus prevents
Propriedades químicas
Consulta técnica sobre: 3D-TAA93771 3-Methyl-1,5-naphthyridine
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