Informação sobre produto
Methyl 3-amino-2-chloro-6-fluorobenzoate is an inhibitor of the enzyme b-raf, which is a protein that plays an important role in cell proliferation and differentiation. Methyl 3-amino-2-chloro-6-fluorobenzoate has been shown to be effective in the treatment of melanoma, as well as other cancerous tumors. The compound inhibits the activity of b-raf by binding to the active site and blocking its function. The binding of methyl 3-amino-2-chloro-6-fluorobenzoate to b -raf decreases phosphorylation of protein kinase B (PKB) and glycogen synthase kinase 3 beta (GSK3β). This leads to decreased activation of downstream effectors such as cyclin D1 and caspases, which are proteins that regulate cell cycle progression and apoptosis respectively.
Propriedades químicas
Consulta técnica sobre: 3D-TAC83074 Methyl 3-amino-2-chloro-6-fluorobenzoate
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