dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate
CAS: 19872-91-4
Ref. 3D-UAA87291
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Informação sobre produto
- Dimethyl 4-Hydroxypyridine-2,6-Dicarboxylate
- 4-Oxo-1H-pyridine-2,6-dicarboxylic acid dimethyl ester
- Dimethyl 4-oxo-1H-pyridine-2,6-dicarboxylate
- Dimethyl 4-Oxo-1,4-Dihydropyridine-2,6-Dicarboxylate
- 2,6-Dimethyl 4-hydroxypyridine-2,6-dicarboxylate
- 4-Hydroxy-pyridine-2,6-dicarboxylic acid dimethyl ester
Dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate is a histone deacetylase inhibitor. It binds to the active site of the enzyme's zinc atom and prevents the removal of acetyl groups from lysine residues on histones. Dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate stabilizes nucleosomal DNA in cells and prevents DNA damage. It is also an apoptotic agent that can induce cell death by inhibiting protein synthesis. This molecule has a protonated water molecule as a tautomer and two hydroxy groups that may be protonated or deprotonated depending on pH conditions. The sulfoxide group is susceptible to oxidation reactions.
Propriedades químicas
Consulta técnica sobre: 3D-UAA87291 dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate
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