GSK189254A

CAS: 720690-73-3

Ref. 3D-VDB69073

Informação sobre produto

• Nome: GSK189254A
• Sinónimos: 6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide, 3-Pyridinecarboxamide, 6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-, GSK 189254A, GSK 189254 free base

Descrição

GSK189254A is a drug that is a novel, potent, and selective H3 receptor antagonist. GSK189254A has a high affinity for the H3 receptor and can be used to treat chronic diseases such as schizophrenia and Alzheimer's disease. GSK189254A has been shown to block histamine-induced increases in striatal dopamine concentration in rats. It also blocks 3-methoxyphenylacetic acid binding to the H3 receptor with an IC50 of 1 nM. GSK189254A has undergone clinical trials in humans and was found to have pharmacokinetic properties similar to other established drugs that are used for the treatment of schizophrenia.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 351.44 g/mol
• Fórmula: C₂₁H₂₅N₃O₂
• Pureza: Min. 95%