Bisindolylmaleimide X hydrochloride
CAS: 145317-11-9
Ref. 3D-VFA31711
1mg | Descontinuado | ||
5mg | Descontinuado | ||
10mg | Descontinuado | ||
25mg | Descontinuado | ||
50mg | Descontinuado |
Informação sobre produto
Bisindolylmaleimide X hydrochloride (BIM-X) is a nitric oxide donor that has been shown to produce vasodilation and regulate blood pressure. BIM-X activates the cation channel, which allows for the influx of calcium into cells. This leads to an increase in fatty acid mobilization, which may be due to a decrease in lipoprotein lipase activity. The increased calcium levels also activate protein kinase C, leading to cell proliferation and differentiation. BIM-X has been shown to induce apoptosis in skin cancer cells in vitro and hepatocyte-like cells in vivo. It also inhibits tumor growth by inducing apoptosis and inhibiting tumor cell proliferation. BIM-X is able to inhibit the activation of myosin phosphatase and can be used as a treatment for diabetic neuropathy, cervical cancer, and apical pancreatitis.