rac-Pregabalin N-acrylamide

CAS: 1495844-28-4

Ref. 3D-VJC84428

Informação sobre produto

• Nome: rac-Pregabalin N-acrylamide
• Marca: Biosynth
• Descrição: Pregabalin is an anticonvulsant drug that is used to treat epilepsy, neuropathic pain, and generalized anxiety disorder. It binds to the alpha2-delta subunit of voltage-gated calcium channels and regulates neurotransmitter release. Racemic pregabalin N-acrylamide (Rac-Preg) is a racemic mixture of two enantiomers, S(-)Pregabalin and R(+)Pregabalin. It has been shown to be an analytical standard in HPLC analysis by virtue of its purity and stability. Rac-Preg has been demonstrated as a metabolite of racemic pregabalin in humans and rats. Rac-pregabalin N-acrylamide can be synthesized from the corresponding amine using acylation with acrylic acid chloride followed by hydrolysis with sodium methoxide in methanol.

Propriedades químicas

• Peso molecular: 213.27 g/mol
• Fórmula: C₁₁H₁₉NO₃
• Pureza: Min. 95%