Cefazolin, Antibiotic for Culture Media Use Only

CAS: 25953-19-9

Ref. 3D-W-107209

Informação sobre produto

• Nome: Cefazolin, Antibiotic for Culture Media Use Only
• Sinónimos: Elzogram 7-(1H-Tetrazol-1-ylacetamido)-3-(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid
• Marca: Biosynth
• Descrição: Cefazolin is a semi-synthetic, non-beta lactam antibiotic used for the treatment of a variety of bacterial infections. It inhibits cell wall synthesis by binding to one or more of penicillin-binding proteins (PBPs), which are bacterial transpeptidases that crosslink peptidoglycan strands. Cefazolin binds to PBPs present on the surface of all Gram-negative bacteria as well as many Gram-positive bacteria. It is not effective against methicillin-resistant staphylococcus and MRSA unless combined with another antibiotic such as vancomycin or flucloxacillin. A study showed that cefazolin can decrease inflammation and tumor necrosis factor-beta levels in pregnant women with systemic inflammatory disease. It has been tested in the development of an anti-inflammatory agent for use in patients with autoimmune diseases such as rheumatoid arthritis and lupus erythe.

Propriedades químicas

• Peso molecular: 454.51 g/mol
• Fórmula: C₁₄H₁₄N₈O₄S₃