Informação sobre produto
- (2R)-amino(thiophen-2-yl)ethanoic acid
- (2S)-amino(thiophen-2-yl)ethanoic acid
- 2-(Thiophen-2-yl)glycine
- 2-Amino-2-(2-Thienyl)acetic acid
- 2-Amino-2-(thiophen-2-yl)acetic acid
- 2-Thiopheneacetic acid, α-amino-
- 2-Thiopheneacetic acid, α-amino-, <span class="text-smallcaps">DL</span>-
- <span class="text-smallcaps">DL</span>-2-Amino-2-thien-2-ylacetic acid
- <span class="text-smallcaps">DL</span>-2-Thienylglycine
- <span class="text-smallcaps">DL</span>-α-Amino-2-thienylacetic acid
- Ver mais sinónimos
- <span class="text-smallcaps">DL</span>-α-Amino-2-thiopheneacetic acid
- Amino(Thiophen-2-Yl)Acetic Acid
- Dl-alpha-aminothiophene-2-acetic acid
- alpha-(2-Thienyl)glycine
- α-Amino-2-thienylacetic acid
- α-Amino-2-thiopheneacetic acid
- 2-Thiopheneacetic acid, α-amino-, DL-
- DL-2-Amino-2-thien-2-ylacetic acid
D-2-Amino-thiopheneacetic acid (DAT) is a non-selective endothelin receptor antagonist. It has an IC50 value of 2 nM for bq-123, an affinity that is mediated by receptor subtypes, and inhibits cyclic AMP production in the presence of hexapeptide. DAT was discovered as a cyclic peptide antagonist of the endothelin receptor. It binds to the same site on the endothelin receptor as endothelin itself, preventing it from binding to its receptors on cells in the body. This prevents activation of cellular responses to endothelin, such as vasoconstriction, which can lead to high blood pressure and heart disease. DAT also has been shown to have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.
Propriedades químicas
Consulta técnica sobre: 3D-WAA12440 DL-±-Amino-2-thiopheneacetic acid
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