1-(Pyrrolidin-2-ylmethyl)-1H-pyrazole
CAS: 1171334-97-6
Ref. 3D-WWB33497
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Informação sobre produto
The compound 1-(pyrrolidin-2-ylmethyl)-1H-pyrazole is a low-molecular-weight pyrazole analogue that has been shown to be an effective chemotherapeutic agent for the treatment of cancer, specifically in lung and breast cancers. It is synthesized by alkylation with 2-(trimethylsilyl)ethanol and methyl iodide in the presence of copper (II) chloride to form 1-(pyrrolidin-2-ylmethyl)-1H-pyrazole. The product was purified by recrystallization from ethyl acetate and ethanol. This compound is a multigram synthetic template for the synthesis of imidazoles, triazoles, and pyrazoles. Deprotection of the hydroxymethyl group at position 4 yields the corresponding amine or alcohol. Hydrophilic substituents are tolerated on position 3, while bulky groups are tolerated on positions 1
Propriedades químicas
Consulta técnica sobre: 3D-WWB33497 1-(Pyrrolidin-2-ylmethyl)-1H-pyrazole
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