Imatinib meta-methyl-piperazine impurity
CAS: 1246819-59-9
Ref. 3D-WZB81959
10mg | Descontinuado | ||
25mg | Descontinuado | ||
50mg | Descontinuado | ||
100mg | Descontinuado | ||
250mg | Descontinuado |
Informação sobre produto
Imatinib is a drug product that has been shown to have significant anticancer activity in the treatment of chronic myeloid leukemia and some other cancers, including gastrointestinal stromal tumor. Imatinib is an orally active tyrosine kinase inhibitor with a half-life of 5-6 hours. It is metabolized to a methyl-piperazine impurity, which is identified as an analytical standard for HPLC analysis. The impurity has been shown to be naturally occurring and also results from metabolism studies in rats and humans. Imatinib is not included in the pharmacopoeia because it has not yet been approved for use in any country.