4-((4-(Allyloxy)phenyl)sulfonyl)phenol

CAS: 97042-18-7

Ref. 3D-XDA04218

Informação sobre produto

• Nome: 4-((4-(Allyloxy)phenyl)sulfonyl)phenol
• Sinónimos: 4'-Allyloxyphenylsulfonyl-4-phenol, 4-Allyloxy-4'-hydroxydiphenylsulfone, 4-Hydroxy-4'-allyloxy diphenyl sulfone, 4-[[4-(2-Propen-1-yloxy)phenyl]sulfonyl]phenol, 4-[[4-(Allyloxy)phenyl]sulfonyl]phenol, Bis(4-hydroxyphenyl)sulfone monoallyl ether, Bis-Mae, Bps-Mae, Phenol, 4-[[4-(2-propenyloxy)phenyl]sulfonyl]-, Phenol,4-[[4-(2-propenyloxy)phenyl]sulfonyl]- (9CI), Phenol, 4-[[4-(2-propen-1-yloxy)phenyl]sulfonyl]-

Descrição

4-((4-(Allyloxy)phenyl)sulfonyl)phenol (4APPSP) is a supramolecular compound that has been shown to bind and activate the estrogen receptor α. The binding affinity of 4APPSP for the estrogen receptor α was evaluated in vitro by radioligand binding assays. 4APPSP binds to the receptor with high affinity and potency, with median concentrations of 0.5 nM and 1 nM, respectively. It also binds to other nuclear receptors with varying degrees of affinity. In vivo studies have not yet been conducted on 4APPSP’s effects on humans, but it has been shown to be effective in biochemical and cell-based assays in yeast, zebrafish, mice, and rats. 4APPSP may be useful as a potential treatment for breast cancer or other estrogen-dependent cancers.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 290.33 g/mol
• Fórmula: C₁₅H₁₄O₄S
• Pureza: Min. 95%