86-MM0836.00-0250 - ursodeoxycholic-acid | 128-13-2

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA) is a potent inhibitor of liver-specific fatty acid transporter 5 (FATP5),inhibits cholesterol absorption. High-Quality, Low-Cost!

<p>Ursodeoxycholic acid</p>

Ursodeoxycholic Acid

<p>Applications Used as an anticholelithogenic. Epimer with Chenodiol with respect to the hydroxyl group at C7.<br>References Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986), Poupon, R.E, et al.: N. Engl. J. Med., 324, 1548 (1991), MacKenzie, P., et al.: J. Biol. Chem., 283, 36205 (2008),<br></p>

<p>Ursodeoxycholic acid is a secondary bile acid, which is derived from the metabolism of primary bile acids by intestinal bacteria. It modifies the composition of bile and reduces the absorption of cholesterol in the gastrointestinal tract by decreasing the cholesterol saturation of bile. This leads to a solubilization of cholesterol gallstones, making it an essential therapeutic agent in the management of cholesterol gallstone disease.</p>

<p>Ursodeoxycholic acid is a naturally occurring bile acid, which is synthesized in the liver from cholesterol. It functions primarily to reduce cholesterol absorption in the intestine and dissolve cholesterol gallstones. This mechanism involves changing the composition of bile and reducing the cholesterol saturation in bile, which reduces micellar cholesterol and bile acid pool size, limiting stone formation.</p>

URSODEOXYCHOLIC ACID CRS

URSODEOXYCHOLIC ACID FOR SYSTEM SUITABILITY CRS

Ursodeoxycholic acid impurity standard