AC-24197 - 5-fluoro-2-nitrophenol-99 | 446-36-6

<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>

5-Fluoro-2-nitrophenol

<p>5-Fluoro-2-nitrophenol is a synthetic compound that has been shown to inhibit the production of nitric oxide in cells. It is most active in inhibiting the release of nitric oxide from cells, but also inhibits its synthesis. 5-Fluoro-2-nitrophenol has been shown to inhibit the production of thromboxane A2, prostacyclin, and endothelin 1. This drug also binds to bacteria and prevents their growth by inhibiting protein synthesis. The binding of 5-fluoro-2-nitrophenol to bacterial DNA leads to inhibition of transcription and translation, preventing protein synthesis.<br>5-Fluoro-2-nitrophenol has been shown to be effective against Trichophyton mentagrophytes (a fungus) and may be useful for the treatment of onychomycosis (fungal infection).</p>