AC-31901 - osmium-tetroxide-4-wt-solution-in-water | 20816-12-0

Applications Osmium Tetroxide (4% in H2O) is a reagent that is used in the dihydroxylation process in the synthesis of 3-[1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy]-1,2-propanediol (D436535). 3-[1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy]-1,2-propanediol is involved in biological studies as microsomal cytochrome P 450 isoenzymes from Penicillium italicum interaction with sterol demethylation inhibitor fungicides.
References Guan, J., et al.: Pest. Biochem. Physiol., 42, 24 (1992);

Oxidation, catalyst in Sharpless dihydroxylations Osmium(VIII) oxide is used in the Sharpless oxyamination to give vicinal amino-alcohols. It is used to oxidize alkenes to the vicinal diols. It acts as a staining agent used in transmission electron microscopy to provide contrast to the image and as