AC-46432 - carteolol-hydrochloride | 51781-21-6

Carteolol hydrochloride

Lactams, nesoi

Carteolol hydrochloride is a nonselective beta-blocker used to treat hypertension, arrhythmias, angina, and glaucoma.

<p>Applications β-Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic; antiglaucoma.<br>References Nakagawa, K., et al.: J. Med. Chem., 17, 529 (1974), Morita, S., et al.: Biochem. Pharmacol., 25, 1836 (1976), Chu, S.Y., et al.: J. Pharm. Sci., 67, 1623 (1978), Chiba, S., et al.: Arzneim.-Forsch., 29, 895 (1979), Chrisp, P., et al.: Drugs Aging, 2, 58 (1992),<br></p>

Carteolol is a beta-adrenergic receptor blocking agent that slows the heart rate and lowers blood pressure. It is used to treat high blood pressure, arrhythmias, and glaucoma. Carteolol hydrochloride is an ester prodrug of carteolol that undergoes hydrolysis by esterases to release carteolol in vivo. This drug also has been shown to have beneficial effects on neuronal death in vitro, although it may have adverse effects on human body formation in vivo.

CARTEOLOL FOR SYSTEM SUITABILITY CRS