Brazilin

CAS: 474-07-7

Ref. BP-BP0281

Informação sobre produto

• Nome: Brazilin
• Sinónimos: (6AS,11bR)-7,11b-dihydro-6H-indeno[2,1-c]chromene-3,6a,9,10-tetrol, (6aS,11bR)-7,11b-Dihydrobenz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol, (6aS,11bR)-7,11b-dihydroindeno[2,1-c]chromene-3,6a,9,10(6H)-tetrol, 7,11b-dihydrobenz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol, 7,11b-dihydroindeno[2,1-c]chromene-3,6a,9,10(6H)-tetrol, Benz(b)indeno(1,2-d)pyran-3,6a,9,10(6H)-tetrol, 7,11b-dihydro- (VAN) (8CI)(9CI), Benz(b)indeno(1,2-d)pyran-3,6a,9,10(6H)-tetrol, 7,11b-dihydro-, (6aS,11bR)-, Benz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol, 7,11b-dihydro-, (6aS-cis)-, Brasilin, Brasiline, Braziletto, Hypernic extract, Limawood extract, Nsc 56652, Nsc 8661, Pernambuco extract, Superbresiline

Descrição

Brazilin, isolated from Caesalpinia sappan has been known as a natural red pigment, exhibits the inhibitory effect on lipopolysaccharide (LPS)-stimulated NO production in a dose-dependent manner (IC50=24.3 microM), might be associated with the regulation of transcription factors NF-kappaB and AP-1; inducible isoform of nitric oxide synthase (NOS) plays an important role in inflammation and carcinogenesis, suggests that the suppressive effect of iNOS gene expression by brazilin might provide one possible mechanism for its anti-inflammatory and cancer chemopreventive activity.

• Marca: Biopurify

Propriedades químicas

• Peso molecular: 286.283
• Fórmula: C₁₆H₁₄O₅
• Pureza: 95%~99%
• Cor/forma: Red powder