SURF-1 rabbit pAb

Ref. EK-ES3527

Informação sobre produto

• Nome: SURF-1 rabbit pAb
• Sinónimos: SURF1; SURF-1; Surfeit locus protein 1

Descrição

This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008],

• Marca: ELK Biotechnology