GlyRβ rabbit pAb

Ref. EK-ES5566

Informação sobre produto

• Nome: GlyRβ rabbit pAb
• Sinónimos: GLRB; Glycine receptor subunit beta; Glycine receptor 58 kDa subunit

Descrição

This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

• Marca: ELK Biotechnology