IGF-IR (phospho Tyr1346) rabbit pAb

Ref. EK-ES5848

Informação sobre produto

• Nome: IGF-IR (phospho Tyr1346) rabbit pAb
• Sinónimos: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Descrição

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

• Marca: ELK Biotechnology