Cyclo(L-Pro-L-Val)

CAS: 2854-40-2

Ref. TM-T125120

Informação sobre produto

• Nome: Cyclo(L-Pro-L-Val)
• Sinónimos: Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-3-(1-methylethyl)-, (3S-trans)-, Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-3-isopropyl-, (S,S)- (8CI), (-)-(6S,9S)-Cyclo(prolylvalyl), Cyclo(L-Val-L-Pro), Cyclo(L-prolyl-L-valine), Cyclo(L-prolyl-L-valyl), L-Valyl-L-prolyl lactam, Maculosin 5, cyclo(Pro-Val)
• CAS: 2854-40-2

Descrição

Cyclo(L-Pro-L-Val), a 2,5-diketopiperazine extracted from the fruits of Mycobacterium chiliolyticum AZ2 and Mycobacterium leprae, possesses anti-inflammatory activity and virulence activity against phytopathogenic microorganisms (e.g., R. fascians LMG 3605) and inhibits Gram-positive plant pathogens.Cyclo(L-Pro-L-Val) significantly inhibited IKKα phosphorylation and IκBα and NF-κB activation as well as iNOS and COX-2 activation in a concentration Cyclo(L-Pro-L-Val) significantly inhibited the phosphorylation of IKKα, IKKβ, IκBα, and NF-κB, as well as the activation of iNOS and COX-2 in a concentration-dependent manner, and is a potential therapeutic agent for the treatment of inflammation-related diseases.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 196.25
• Fórmula: C₁₀H₁₆N₂O₂
• Pureza: 98.18%
• Cor/forma: Solid