Bufalin

CAS: 465-21-4

Ref. TM-T1719

Informação sobre produto

• Nome: Bufalin
• Sinónimos: (3Beta,5Beta,8Xi,9Xi)-3,14-Dihydroxybufa-20,22-Dienolide, (3β,5β)-3,14-Dihydroxybufa-20,22-dienolide, 3,14-Dihydroxybufa-20,22-Dienolide, 5β-Bufa-20,22-dienolide, 3β,14-dihydroxy-, B 0261, Bufa-20,22-dienolide, 3,14-dihydroxy-, (3β,5β)-, NSC 89595
• CAS: 465-21-4

Descrição

Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic activity. Although the mechanism of action of bufalin is still under investigation, this agent is a specific Na+/K+-ATPase inhibitor and can induce apoptosis in Y cell lines through the activation of the transcription factor AP-1 via a mitogen activated protein kinase (MAPK) pathway.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 386.52
• Fórmula: C₂₄H₃₄O₄
• Pureza: 99.25%
• Cor/forma: White Solid