Semaxinib
CAS: 204005-46-9
Ref. TM-T2064
5mg | 52,00 € | ||
10mg | 66,00 € | ||
25mg | 117,00 € | ||
50mg | 164,00 € | ||
100mg | 220,00 € | ||
1ml*10 (DMSO) | 54,00 € |
Informação sobre produto
- SU5416
- (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one
- (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
- (Z)-3-(3,5-Dimethylpyrrol-2-ylmethylene)indolin-2-one
- 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-
- 3-((2,4-Dimethylpyrrol-5-YL)METHYLIDENYL)-2-indolonone
- 3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-1,3-dihydroindol-2-one
- 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
- 3-[(3,5-Dimethylpyrrol-2-yl)methylene]indolin-2-one
- Nsc-696819
- Ver mais sinónimos
- Semaxanib
- Semoxind
- Su-5416
- Sugen 5416
- Tsu-16
- VEGFR2 receptor tyrosine kinase III
Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR than PDGFRβ, lack of activity against InsR, EGFR, and FGFR. Semaxanib reversibly inhibits ATP binding to the tyrosine kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2), which may inhibit VEGF-stimulated endothelial cell migration and proliferation and reduce the tumor microvasculature.
Propriedades químicas
Consulta técnica sobre: TM-T2064 Semaxinib
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