Mollugin

CAS: 55481-88-4

Ref. TM-T3673

Informação sobre produto

• Nome: Mollugin
• Sinónimos: Rubimaillin, 2H-naphtho[1,2-b]pyran-5-carboxylic acid, 6-hydroxy-2,2-dimethyl-, methyl ester, Methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate, Smb 00431
• CAS: 55481-88-4

Descrição

Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 284.31
• Fórmula: C₁₇H₁₆O₄
• Pureza: 98.31%
• Cor/forma: Solid