Mitoxantrone

CAS: 65271-80-9

Ref. TM-T6588

Informação sobre produto

• Nome: Mitoxantrone
• Sinónimos: mitozantrone, 1,4-Bis[(2-(2-hydroxyethylamino)ethyl)amino]-5,8-dihydroxyanthraquinone, 1,4-Dihydroxy-5,8-bis-[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone, 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione, Dhaq, Dihydroxyanthraquinone, Mitox, Mitoxanthrone, Mitozantrone, Nimitoxantron, Novantron, Novantrone, Nsc 279836, Ralenova
• CAS: 65271-80-9

Descrição

Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 444.48
• Fórmula: C₂₂H₂₈N₄O₆
• Pureza: 98.14%
• Cor/forma: Blue Powder
• InChI: InChI=1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2
• Chave InChI: InChIKey=KKZJGLLVHKMTCM-UHFFFAOYSA-N
• SMILES: O=C1c2c(O)ccc(O)c2C(=O)c2c(NCCNCCO)ccc(NCCNCCO)c21