KW-2450 free base

CAS: 904899-25-8

Ref. TM-T68405

Informação sobre produto

• Nome: KW-2450 free base

Descrição

KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 515.63
• Fórmula: C₂₈H₂₉N₅O₃S
• Pureza: 99.11%
• Cor/forma: Solid