NecroX-7

CAS: 1120332-55-9

Ref. TM-T9948

Informação sobre produto

• Nome: NecroX-7
• Sinónimos: LC-280126, LC28-0126, LC28 0126
• CAS: 1120332-55-9

Descrição

NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. Additionally, NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 may be use for treatment of graft-versus-host disease (GVHD) research [1].

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 439.57
• Fórmula: C₂₄H₂₉N₃O₃S
• Pureza: 98.08%
• Cor/forma: Solid