ACVR2B Protein, Human, Recombinant (hFc & His)
Ref. TM-TMPJ-00314
1mg | 1.888,00 € | ||
10µg | 70,00 € | ||
50µg | 185,00 € | ||
500µg | 1.368,00 € |
Informação sobre produto
- ACVR2B, Activin Receptor Type IIB, ACTR-IIB, Activin Receptor Type-2B
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, also known as ActRIIB, is a type II receptor containing an extracellular domain (ECD), a transmembrane segment, and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A, activin B and inhibin A. Multiple ActRIIB isoforms can also be generated, which bind activin isoforms with different affinities.
Propriedades químicas
Consulta técnica sobre: TM-TMPJ-00314 ACVR2B Protein, Human, Recombinant (hFc & His)
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