NCK1 Protein, Human, Recombinant (His)

Ref. TM-TMPJ-00870

Informação sobre produto

• Nome: NCK1 Protein, Human, Recombinant (His)
• Sinónimos: SH2/SH3 Adaptor Protein NCK-α, SH2/SH3 Adaptor Protein NCK-Alpha, Nck-1, Cytoplasmic Protein NCK1, NCK, NCK adaptor Protein 1, NCK1

Descrição

Cytoplasmic Protein NCK1 (NCK1) is a cytoplasmic protein that contains one SH2 domain and three SH3 domains. NCK1 is a member of the adapter family, which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. NCK1 maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. NCK1 plays a role in the DNA damage response, but not in the detection of the damage by ATM/ATR. It is also involved in transducing signals from receptor tyrosine kinases to downstream signal recipients, such as ELK1-dependent transcriptional activation in response to activated Ras signaling.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 50 KDa (reducing condition)
• Cor/forma: Solid