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B7-1 Protein, Rabbit, Recombinant (His)
Ref. TM-TMPJ-00958
1mg | 1.107,00 € | ||
10µg | 70,00 € | ||
50µg | 115,00 € | ||
500µg | 796,00 € |
Informação sobre produto
- Activation B7-1 antigen, T-lymphocyte activation antigen CD80, B7, CD80
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response.
Propriedades químicas
Consulta técnica sobre: TM-TMPJ-00958 B7-1 Protein, Rabbit, Recombinant (His)
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