Mucin-17/MUC17 Protein, Human, Recombinant (His)

Ref. TM-TMPJ-01456

Informação sobre produto

• Nome: Mucin-17/MUC17 Protein, Human, Recombinant (His)
• Sinónimos: Mucin-17, MUC-17, MUC17, MUC3, MUC-3

Descrição

Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients. And that p38 signalling is a key factor involved in MUC17-mediated inhibition of GC cell proliferation and protection against inflammatory stimulation, MUC17 upregulates the expression of MYH9 and p53, and activates the p38 pathway in GC cells through RhoA signalling.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 45-55&25-30&17-21 kDa (reducing condition)
• Cor/forma: Solid